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Astelin

  • $30.46AUD
  • Availability: In Stock
  • Active Ingredient Azelastine
Astelin is an antihistamine nasal spray used to treat allergy symptoms such as sneezing and itchy, runny nose.

10 ml
Product name Per Pill Per Pack  
1 sprayer $44.15AUD $44.15AUD
2 sprayer $36.55AUD $88.30AUD $73.09AUD
3 sprayer $34.01AUD $132.45AUD $102.04AUD
4 sprayer $32.74AUD $176.60AUD $130.98AUD
5 sprayer $31.98AUD $220.75AUD $159.92AUD
6 sprayer $31.48AUD $264.90AUD $188.86AUD
7 sprayer $31.12AUD $309.05AUD $217.81AUD
8 sprayer $30.84AUD $353.20AUD $246.75AUD
9 sprayer $30.63AUD $397.35AUD $275.69AUD
10 sprayer $30.46AUD $441.50AUD $304.64AUD

Product Description

Common use
Astelin is an antihistamine nasal spray which is used to treat allergy symptoms such as sneezing and itchy, runny nose. This medication works by blocking the action of histamine, which reduces allergy symptoms. Also Astelin is used for treating such symptoms as runny nose or stuffy nose, and postnasal drip.

Dosage and direction

Astelin should be used for nose only, so please avoid contacting with eyes. Blow your nose before using this medication. The recommended starting dose is 4 sprays a day. After three days the recommended dose is 2 sprays a day.
Note: this instruction is presented here just for a review. It's very necessary to consult your doctor before using. It will help you to get best results.

Precautions

Use with cautions if your medical history include: allergies, heart disease, kidney problems,high blood pressure, liver problems. Using Astelin with alcohol or CNS depressants can increase side effects. Astelin should not be used during pregnancy, lactation or when becoming pregnant. Do not use Astelin before breast-feeding without a doctor's permission.

Contraindications

Astelin is not allowed to people with: allergy to any antihistamines; narrow angle glaucoma; bladder neck obstruction; symptomatic prostatic hypertrophy; asthmatic attack; stenosing peptic ulcer; pyloroduodenal obstruction. Atelin should not be used in neonates (possible association with SIDS)

Possible side effect

They may include an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Also the most possible side effects include:
bronchospasm (shortness of breath, tightness in chest, wheezing);
fast or uneven heartbeats.
Less serious include:
a bitter taste in your mouth;
headache;
drowsiness or dizziness;
dry mouth, sore throat;
burning in your nose;
weight gain;
nausea;
nosebleed;
cough, sneezing, runny nose, cold symptoms; or
eye redness.
If you experience one of them stop using Astelin and tell your doctor as soon as possible. Also consult your doctor about any side effect that seems unusual.

Drug interaction

Astelin interact with such medication as: cimetidine, sleep medicines, sedatives, tranquilizers, drugs for anxiety, narcotic pain relievers, antidepressants or other psychiatric drugs, other antihistamines. Also note that interaction between two medications does not always mean that you must stop taking one of them. As usual it affects the effect of drugs, so consult your doctor about how these interactions are being managed or should be managed.

Missed dose

If you forgot to take your dose in time, please do it as soon as you remember. But do not take if it is too late or almost time for your next dose. Do not take double or extra doses. Take your usual dose next day at the same regularly time.

Overdose

Symptoms of an Astelin overdose are unknown, but possibly may include extreme sleepiness. If you experience one of them or if you experience any unusual symptom call your doctor immediately.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Store away from heat, moisture, and light. Do not store in the bathroom. Keep the bottle upright with the pump tightly closed. Protect from freezing.
Keep out of the reach of children.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.

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Following the safety recommendations and taking into consideration contraindications, warnings and precautions will decrease the risk of experiencing unwanted reactions and side effects. However, patients, who are hypersensitive to the components of the drug, can witness mild to severe adverse reactions listed below. Contact your doctor or online medical specialist to eliminate the risk of serious consequences. Seek medical assistance the moment you have noticed the following side effects:

Rare

  • Blood in the urine
  • blurred vision or other change in vision
  • cough
  • eye pain
  • eye redness
  • hives, itching, or skin rash
  • rapid heartbeat
  • sores in the mouth or on the lips
  • tightness in the chest
  • troubled breathing

More Common

  • Bitter taste in the mouth
  • drowsiness or sleepiness

Less Common

  • Bloody mucus or unexplained nosebleeds
  • burning inside the nose
  • dizziness
  • dryness of the mouth
  • headache
  • muscle aches or pain
  • nausea
  • sore throat
  • sudden outbursts of sneezing
  • unusual tiredness or weakness
  • weight gain
Type Small Molecule
Accession Number DB00972  (APRD00813)
Groups Approved
Synonyms
  • 4-(P-Chlorobenzyl)-2-(hexahydro-1-methyl-1H-azepin-4-yl)-1-(2H)-phthalazinone
  • Azelastina
  • Azelastinum
UNII ZQI909440X
CAS number 58581-89-8
Weight Average: 381.898
Monoisotopic: 381.160790112
Chemical Formula C22H24ClN3O
InChI
InChI=1S/C22H24ClN3O/c1-25-13-4-5-18(12-14-25)26-22(27)20-7-3-2-6-19(20)21(24-26)15-16-8-10-17(23)11-9-16/h2-3,6-11,18H,4-5,12-15H2,1H3
IUPAC Name
4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)-1,2-dihydrophthalazin-1-one
Protein binding

In-vitro studies in human plasma indicate that the plasma protein binding of azelastine and N-desmethylazelastine are approximately 88% and 97%, respectively.

Toxicity Not Available
Half life

Elimination half-life (based on intravenous and oral administration) is 22 hours. Elimination half-life of the active metabolite, desmethylazelastine, is 54 hours (after oral administration of azelastine).

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  • Wollongong