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Citalopram

  • $0.72AUD
  • Availability: In Stock
  • Active Ingredient Citalopram
Citalopram is used for treating depression and may also be used for other conditions as determined by your doctor.
Analogs of Citalopram: Lexapro   Celexa  
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Other names of Citalopram: a   b   c   d   e   f   g   h   i   j   k   l   m   n   o   p   q   r   s   t   u   v   w   x   y   z  
Adeprenal   Alcytam   Apo-Citalopram   Arpolax   Aurex   Abbott-Citalopram   Abgenix   Actipram   Adco-Talomil   Alepram   Alopra   Ansiben   Antidepressa   Apo-Cital   Arrow Citalopram   Auro-Citalopram   Austell-Citalopram   Acelopam   A-Depress-Therapy   Atinorm  
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40 mg
Product name Per Pill Per Pack  
30 pills $3.03AUD $90.99AUD
60 pills $2.40AUD $181.97AUD $144.25AUD
90 pills $2.19AUD $272.96AUD $197.52AUD
120 pills $2.09AUD $363.95AUD $250.79AUD
180 pills $1.99AUD $545.92AUD $357.33AUD
270 pills $1.92AUD $818.89AUD $517.12AUD
360 pills $1.88AUD $1,091.85AUD $676.95AUD
20 mg
Product name Per Pill Per Pack  
60 pills $1.10AUD $65.80AUD
90 pills $0.95AUD $98.69AUD $85.27AUD
120 pills $0.87AUD $131.59AUD $104.75AUD
180 pills $0.80AUD $197.39AUD $143.69AUD
270 pills $0.75AUD $296.08AUD $202.12AUD
360 pills $0.72AUD $394.78AUD $260.54AUD

Drug Uses

Citalopram is used for treating depression. It may also be used for other conditions as determined by your doctor.

How to use

Use Citalopram as directed by your doctor.

Drug Class and Mechanism

Citalopram is a selective serotonin reuptake inhibitor (SSRI). It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems.

Missed Dose

If you miss a dose of Citalopram, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Citalopram at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Keep Citalopram out of the reach of children and away from pets.

Warnings/Precautions

Do not use Citalopram if:

you are allergic to any ingredient in Citalopram;
you are taking escitalopram;
you are taking or have taken a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine), selegiline, or St. John's wort within the last 14 days;
you are taking a fenfluramine derivative (e.g., dexfenfluramine), an H1 antagonist (e.g., astemizole, terfenadine), nefazodone, pimozide, or sibutramine.
Contact your doctor or health care provider right away if any of these apply to you.

Important:

Citalopram may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Citalopram with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Do not drink alcohol while you are using Citalopram.
Check with your doctor before you use medicines that may cause drowsiness (e.g., sleep aids, muscle relaxers) while you are using Citalopram; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
One to 4 weeks may pass before your symptoms improve. Do not take more than the recommended dose, change your dose, or use Citalopram for longer than prescribed without checking with your doctor.
Children, teenagers, and young adults who take Citalopram may be at increased risk for suicidal thoughts or actions. Watch all patients who take Citalopram closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
Citalopram and a medicine called escitalopram have the same active ingredient. Do not take Citalopram if you are also taking escitalopram.
Citalopram may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

Decreased sexual desire or ability; diarrhea; dizziness; drowsiness; dry mouth; increased sweating; lightheadedness when you stand or sit up; loss of appetite; nausea; stuffy nose; tiredness.

Seek medical attention right away if any of these severe side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); absent menstrual period; bizarre behavior; black or bloody stools; chest pain; confusion; decreased concentration; fast or irregular heartbeat; hallucinations; memory loss; new or worsening agitation, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, or inability to sit still; persistent, painful erection; red, swollen, blistered, or peeling skin; seizures; severe or persistent anxiety or trouble sleeping; stomach pain; suicidal thoughts or attempts; tremor; unusual bruising or bleeding; unusual or severe mental or mood changes; vision changes; worsening of depression.

More Information

Citalopram is to be used only by the patient for whom it is prescribed. Do not share it with other people.

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Following the safety recommendations and taking into consideration contraindications, warnings and precautions will decrease the risk of experiencing unwanted reactions and side effects. However, patients, who are hypersensitive to the components of the drug, can witness mild to severe adverse reactions listed below. Contact your doctor or online medical specialist to eliminate the risk of serious consequences. Seek medical assistance the moment you have noticed the following side effects:

Rare

  • Behavior change similar to drunkenness
  • bleeding gums
  • breast tenderness or enlargement or unusual secretion of milk (in females)
  • chills
  • convulsions (seizures)
  • diarrhea
  • difficulty with concentrating
  • dizziness or fainting
  • drowsiness
  • increased hunger
  • increased thirst
  • irregular heartbeat
  • lack of energy
  • lethargy
  • nosebleed
  • overactive reflexes
  • painful urination
  • poor coordination
  • purple or red spots on the skin
  • rapid weight gain
  • red or irritated eyes
  • redness, tenderness, itching, burning, or peeling of the skin
  • shivering
  • slow or irregular heartbeat (less than 50 beats per minute)
  • sore throat
  • stupor
  • sweating
  • swelling of the face, ankles, or hands
  • talking or acting with excitement you cannot control
  • trembling, shaking, or twitching
  • trouble with holding or releasing urine
  • unusual or sudden body or facial movements or postures
  • unusual tiredness or weakness

More Common

  • Decrease in sexual desire or ability
  • sleepiness or unusual drowsiness

Less Common

  • Agitation
  • blurred vision
  • confusion
  • fever
  • increase in the frequency of urination or amount of urine produced
  • lack of emotion
  • loss of memory
  • menstrual changes
  • skin rash or itching
  • trouble breathing
  • Body aches or pain
  • change in sense of taste
  • gas
  • headache (severe and throbbing)
  • heartburn
  • increased sweating
  • increased yawning
  • loss of voice
  • pain in the muscles or joints
  • sneezing
  • stuffy or runny nose
  • tingling, burning, or prickly feelings on the skin
  • tooth grinding
  • unusual increase or decrease in weight
  • watering of the mouth

Incidence Not Known

  • Abdominal or stomach pain
  • back or leg pains
  • black, tarry stools
  • bloating
  • bloody stools
  • chest pain
  • confusion as to time, place, or person
  • constipation
  • cough
  • darkened urine
  • difficult or fast breathing
  • difficulty with swallowing
  • drooling
  • fast, slow, or irregular heartbeat
  • general body swelling
  • hive-like swelling on the face, eyelids, lips, tongue, or throat
  • hives
  • holding false beliefs that cannot be changed by fact
  • impaired consciousness, ranging from confusion to coma
  • indigestion
  • itching, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • loss of appetite
  • loss of bladder control
  • loss of consciousness
  • muscle cramps or spasms
  • muscle tightness
  • muscle twitching or jerking
  • painful or prolonged erection of the penis
  • pale skin
  • penile erections, frequent or continuing
  • recurrent fainting
  • rhythmic movement of the muscles
  • seeing, hearing, or feeling things that are not there
  • swelling of the breasts or unusual milk production
  • tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
  • tightness in the chest
  • total body jerking
  • twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
  • uncontrolled jerking or twisting movements
  • unusual excitement
  • vomiting of blood or material that looks like coffee grounds
  • yellowing of the eyes or skin
  • Bruising
  • inability to sit still
  • large, flat, blue or purplish patches in the skin
  • need to keep moving
  • uncontrolled eye movements
Type Small Molecule
Accession Number DB00215  (APRD00147)
Groups Approved
Synonyms
  • Citadur
  • Nitalapram
UNII 0DHU5B8D6V
CAS number 59729-33-8
Weight Average: 324.3919
Monoisotopic: 324.163791509
Chemical Formula C20H21FN2O
InChI
InChI=1S/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
IUPAC Name
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
Protein binding

Citalopram, dimethylcitalopram, and didemethylcitalopram is 80% bound to plasma proteins [Label].

Toxicity

Symptoms of toxicity include dizziness, sweating, nausea, vomiting, tremor, somnolence, and sinus tachycardia. Rarely, symptoms included amnesia, confusion, coma, convulsions, hyperventilation, cyanosis, rhabdomyolysis, and ECG changes (including QTc prolongation, nodal rhythm, ventricular arrhythmia, and extremely rare cases of cardiac torsade de pointes) may occur. Acute renal failure has been a rare occurrence [5].

In cases of overdose, establish and maintain the airway to ensure adequate ventilation and oxygen delivery. Due to the large volume of distribution of citalopram, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit. Gastric evacuation by lavage and use of activated charcoal should be considered. Careful observation and cardiac and vital sign monitoring are advised, in addition to supportive care. With the large volume of distribution of citalopram, forced diuresis, dialysis, hemoperfusion, and exchange transfusion are unlikely to be of benefit [Label].

Half life

35 hours [Label].

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