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Actonel

  • $7.84AUD
  • Availability: In Stock
  • Active Ingredient risedronate
Actonel (risedronate) is in a group of medicines called bisphosphonates (bis FOS fo nayts). Risedronate alters the cycle of bone formation and breakdown in the body. Actonel slows bone loss while increasing bone mass, which may prevent bone fractures. Actonel is used to treat or prevent osteoporosis. Actonel is also used to treat Paget's disease of bone.
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Seralis   Sedron  
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35 mg
Product name Per Pill Per Pack  
4 pills $12.06AUD $48.23AUD
8 pills $9.71AUD $96.47AUD $77.71AUD
12 pills $8.93AUD $144.70AUD $107.18AUD
16 pills $8.54AUD $192.93AUD $136.66AUD
20 pills $8.31AUD $241.16AUD $166.14AUD
24 pills $8.15AUD $289.40AUD $195.61AUD
28 pills $8.04AUD $337.63AUD $225.09AUD
32 pills $7.96AUD $385.86AUD $254.56AUD
36 pills $7.89AUD $434.10AUD $284.04AUD
40 pills $7.84AUD $482.33AUD $313.51AUD

INDICATIONS

Actonel (risedronate sodium) tablets is a pyridinyl bisphosphonate that inhibits osteoclast-mediated bone resorption and modulates bone metabolism. Risedronic acid (INN) or risedronate sodium (USAN) is a bisphosphonate used to strengthen bone, treat or prevent osteoporosis, and treat Paget's disease of bone.

INSTRUCTIONS  

Take Actonel exactly as your doctor prescribes. Do not take a Actonel tablet if you cannot sit upright or stand for at least 30 minutes. Actonel can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking this medication.

Take the Actonel tablet first thing in the morning with a full glass (6 to 8 ounces) of water, at least 30 minutes before you eat or drink anything or take any other medicine.

Before taking risedronate, tell your doctor or pharmacist if you are allergic to it; or to other bisphosphonates (e.g., alendronate, etidronate, pamidronate); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.

To make sure you can safely take Actonel, tell your doctor if you have any of these other conditions:
low blood calcium (hypocalcemia);
a vitamin D deficiency;
kidney disease;
an ulcer in your stomach or esophagus.

STORAGE 

Store Actonel at 77 degrees F (25 degrees C). Keep away from heat, moisture, and light. Do not store in the bathroom. Keep Actonel out of the reach of children and away from pets.

SAFETY INFORMATION

Stop using Actonel if:

Stop using risedronate and call your doctor at once if you have any of these serious side effects: chest pain; difficulty or pain when swallowing; pain or burning under the ribs or in the back; new or worsening heartburn; severe joint, bone, or muscle pain; jaw pain, numbness.

Do not take two different strengths of Actonel tablet at the same time.

If you take Actonel only once a week, take it on the same day and time each week.

Do not crush, chew, or suck the Actonel tablet. Swallow the pill whole. The enteric coated pill has a special coating to protect your throat and stomach. Breaking the pill will damage this coating.

If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using Actonel. You may need to stop using the medicine for a short time.

To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. Visit your doctor regularly.

Actonel is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

FDA pregnancy category C. It is not known whether Actonel will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether risedronate passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking Actonel.

SIDE EFFECTS

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using Actonel and call your doctor at once if you have a serious side effect such as:

  • chest pain;
  • difficulty or pain when swallowing;
  • pain or burning under the ribs or in the back;
  • new or worsening heartburn;
  • severe or ongoing indigestion;
  • severe joint, bone, or muscle pain;
  • new or unusual pain in your thigh or hip; 
  • jaw pain, numbness, or swelling.

Less serious Actonel side effects may include:

  • flu symptoms, muscle pain;
  • mild stomach pain or upset stomach;
  • diarrhea, constipation;
  • mild joint or back pain;
  • headache. 
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Following the safety recommendations and taking into consideration contraindications, warnings and precautions will decrease the risk of experiencing unwanted reactions and side effects. However, patients, who are hypersensitive to the components of the drug, can witness mild to severe adverse reactions listed below. Contact your doctor or online medical specialist to eliminate the risk of serious consequences. Seek medical assistance the moment you have noticed the following side effects:

Rare

  • Red, sore eyes
  • Fainting
  • fear
  • itching skin
  • loss of appetite
  • pale skin
  • passing of gas
  • redness, swelling, or soreness of the tongue
  • sneezing
  • stomach fullness
  • tightness in the chest
  • troubled breathing
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • wheezing

More Common

  • Abdominal or stomach pain
  • skin rash
  • Back pain
  • cough or hoarseness
  • diarrhea
  • fever or chills
  • headache
  • joint pain
  • lower back or side pain
  • painful or difficult urination

Less Common

  • Abdominal or stomach pain (severe)
  • belching
  • bone pain
  • cramping of the stomach
  • trouble swallowing
  • Acid or sour stomach
  • bladder pain
  • bloody or cloudy urine
  • blurred vision or change in vision
  • body aches or pains
  • congestion
  • constipation
  • difficult, burning, or painful urination
  • difficulty with moving
  • dizziness
  • dry eyes
  • dryness or soreness of the throat
  • frequent urge to urinate
  • general feeling of discomfort or illness
  • indigestion
  • leg cramps
  • muscle pain or stiffness
  • nausea
  • nervousness
  • pain, swelling, or redness in the joints
  • pounding in the ears
  • ringing in the ears
  • runny nose
  • slow or fast heartbeat
  • stomach discomfort or upset
  • swelling of the feet or lower legs
  • tender swollen glands in the neck
  • voice changes
  • weakness

Incidence Not Known

  • Bone, joint, or muscle pain, severe and occasionally incapacitating
  • chest pain
  • heartburn
  • pain or burning in the throat
  • sores, ulcers, or white spots on the lips or tongue or inside the mouth
  • vomiting
  • Eye pain
  • large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
  • muscle pain
  • redness of the eye
  • sensitivity of the eye to light
  • skin blisters
  • tearing
Type Small Molecule
Accession Number DB00884  (APRD00410, DB02782)
Groups Approved, Investigational
Synonyms
  • Acide risédroniqe
  • Acido risedronico
  • Acidum risedronicum
  • Ridron
  • Risedronate
  • Risedronic acid
  • Risedronsäure
UNII KM2Z91756Z
CAS number 105462-24-6
Weight Average: 283.1123
Monoisotopic: 283.001074735
Chemical Formula C7H11NO7P2
InChI
InChI=1S/C7H11NO7P2/c9-7(16(10,11)12,17(13,14)15)4-6-2-1-3-8-5-6/h1-3,5,9H,4H2,(H2,10,11,12)(H2,13,14,15)
IUPAC Name
[1-hydroxy-1-phosphono-2-(pyridin-3-yl)ethyl]phosphonic acid
Protein binding

~24%

Toxicity

Side effects include abdominal pain, anxiety, back pain, belching, bladder irritation, bone disorders and pain, bronchitis, bursitis, cataracts, chest pain, colitis, constipation, depression, diarrhea, difficulty breathing, dizziness, dry eyes, eye infection, flu-like symptoms, gas, headache, high blood pressure, infection, insomnia, itching, joint disorders and pain, leg cramps, muscle pain, muscle weakness, nausea, neck pain, nerve pain, pain, pneumonia, rash, ringing in ears, sinus problems, sore throat, stomach bleeding, stuffy or runny nose, swelling, tendon problems, tumor, ulcers, urinary tract infection, vertigo, vision problems, and weakness.

Half life

1.5 hours

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  • Sydney
  • Albury
  • Armidale
  • Bathurst
  • Blue Mountains
  • Broken Hill
  • Campbelltown
  • Cessnock
  • Dubbo
  • Goulburn
  • Grafton
  • Lithgow
  • Liverpool
  • Newcastle
  • Orange
  • Parramatta
  • Penrith
  • Queanbeyan
  • Tamworth
  • Wagga Wagga
  • Wollongong