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Afluhist Plus (Brand name: Prednisolone)

  • $0.43AUD
  • Availability: In Stock
  • Active Ingredient
Afluhist Plus is used for treating allergies, arthritis, breathing problems (e.g., asthma), certain blood disorders, collagen diseases (e.g., lupus), certain eye diseases (e.g., keratitis), cancer (e.g., leukemia), endocrine problems (e.g., adrenocortical insufficiency), intestinal problems (e.g., ulcerative colitis), swelling due to certain conditions, or skin conditions (e.g., psoriasis).
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40 mg
Product name Per Pill Per Pack  
30 pills $2.28AUD $68.42AUD
60 pills $1.47AUD $136.85AUD $88.33AUD
90 pills $1.20AUD $205.27AUD $108.23AUD
120 pills $1.07AUD $273.70AUD $128.14AUD
180 pills $0.93AUD $410.55AUD $167.96AUD
270 pills $0.84AUD $615.82AUD $227.67AUD
360 pills $0.80AUD $821.10AUD $287.37AUD
20 mg
Product name Per Pill Per Pack  
60 pills $1.17AUD $70.11AUD
90 pills $0.97AUD $105.17AUD $87.08AUD
120 pills $0.87AUD $140.23AUD $104.05AUD
180 pills $0.77AUD $210.34AUD $138.00AUD
270 pills $0.70AUD $315.51AUD $188.88AUD
360 pills $0.67AUD $420.68AUD $239.79AUD
5 mg
Product name Per Pill Per Pack  
90 pills $0.61AUD $54.68AUD
120 pills $0.55AUD $72.90AUD $65.85AUD
180 pills $0.49AUD $109.35AUD $88.21AUD
270 pills $0.45AUD $164.03AUD $121.74AUD
360 pills $0.43AUD $218.70AUD $155.28AUD
10 mg
Product name Per Pill Per Pack  
60 pills $1.15AUD $68.83AUD
90 pills $0.95AUD $103.24AUD $85.06AUD
120 pills $0.84AUD $137.65AUD $101.31AUD
180 pills $0.74AUD $206.48AUD $133.80AUD
270 pills $0.68AUD $309.72AUD $182.54AUD
360 pills $0.64AUD $412.95AUD $231.24AUD

Drug Uses

Afluhist Plus is used for treating allergies, arthritis, breathing problems (e.g., asthma), certain blood disorders, collagen diseases (e.g., lupus), certain eye diseases (e.g., keratitis), cancer (e.g., leukemia), endocrine problems (e.g., adrenocortical insufficiency), intestinal problems (e.g., ulcerative colitis), swelling due to certain conditions, or skin conditions (e.g., psoriasis). It may also be used for other conditions as determined by your doctor.

How to use

Use Afluhist Plus as directed by your doctor. Check the label on the medicine for exact dosing instructions.

Take Afluhist Plus by mouth with or without food.
Swallow Afluhist Plus whole. Do not break, crush, or chew before swallowing.
Continue taking Afluhist Plus even if you feel good. Do not miss any doses.

Drug Class and Mechanism

Afluhist Plus is a corticosteroid. It works by modifying the body's immune response to various conditions and decreasing inflammation.

Missed Dose

If you miss a dose of Afluhist Plus, skip the missed dose. Go back to your regular dosing schedule. Do not take 2 doses at once.

Storage

Store Afluhist Plus at 77 degrees F (25 degrees C). Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Afluhist Plus out of the reach of children and away from pets.

Warnings/Precautions

Do not use Afluhist Plus if:

you are allergic to any ingredient of Afluhist Plus;
you have a systemic fungal infection, a certain type of malaria, inflammation of the optic nerve, or herpes infection of the eye;
you are scheduled to have a live or attenuated live vaccination (eg, smallpox);
you are taking mifepristone.
Contact your doctor or health care provider right away if any of these apply to you.

Important:

Afluhist Plus may lower the ability of your body to fight infection. Avoid contacts with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
If you have not had chickenpox, shingles, or measles, avoid contact with anyone who does.
If you are taking Afluhist Plus regularly over a long period of time, carry an ID card at all times that says you take Afluhist Plus.
Do not receive a live vaccine (eg, measles, mumps) while you are taking Afluhist Plus . Talk with your doctor before you receive any vaccine.
Tell your doctor or dentist that you take Afluhist Plus before you receive any medical or dental care, emergency care, or surgery.
Diabetes patients - Afluhist Plus may affect your blood sugar. Check blood sugar levels. Ask your doctor before you change the dose of your diabetes medicine.
Lab tests, including adrenal function tests, may be performed while you use Afluhist Plus. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
Caution is advised when using Afluhist Plus in children; they may be more sensitive to its effects.
Corticosteroids may affect growth rate in children and teenagers in some cases. They may need regular growth checks while they take Afluhist Plus.
Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Afluhist Plus while you are pregnant. Afluhist Plus is found in breast milk. If you are or will be breast-feeding while you use Afluhist Plus, check with your doctor. Discuss any possible risks to your baby.

Possible Side Effects

Check with your doctor if any of these most common side effects persist or become bothersome:

acne; clumsiness; dizziness; facial flushing; feeling of a whirling motion; general body discomfort; headache; increased appetite; increased sweating; nausea; nervousness; sleeplessness; upset stomach.
Seek medical attention right away if any of these severe side effects occur:
severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; changes in body fat; changes in menstrual period; changes in skin color; chest pain; easy bruising or bleeding; infection (e.g., fever, chills, sore throat); mental or mood changes (e.g., depression); muscle pain, weakness, or wasting; seizures; severe nausea or vomiting; sudden severe dizziness or headache; swelling of feet or legs; tendon or bone pain; thinning of skin; unusual skin sensation; unusual weight gain; vision changes or other eye problems; vomit that looks like coffee grounds.

More Information

Afluhist Plus is to be used only by the patient for whom it is prescribed. Do not share it with other people.

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Following the safety recommendations and taking into consideration contraindications, warnings and precautions will decrease the risk of experiencing unwanted reactions and side effects. However, patients, who are hypersensitive to the components of the drug, can witness mild to severe adverse reactions listed below. Contact your doctor or online medical specialist to eliminate the risk of serious consequences. Seek medical assistance the moment you have noticed the following side effects:

Incidence Not Known

  • Blindness
  • blurred vision
  • burning, dry, itching eyes
  • change in vision
  • decreased vision
  • difficulty in focusing
  • drooping of the upper eyelids
  • eye discharge, excessive tearing
  • feeling of having something in the eye
  • redness, irritation, pain, swelling of the eye, eyelid, or inner lining of the eyelid
  • sensitivity of the eye to light
  • slow wound healing
  • Change in taste
  • headache
  • loss of taste
Type Small Molecule
Accession Number DB00860  (APRD00197)
Groups Approved, Vet approved
Synonyms
  • (11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
  • 1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
  • 1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
  • 3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
  • delta-dehydrocortisol
  • delta-dehydrohydrocortisone
  • delta-hydrocortisone
  • delta(1)-Dehydrocortisol
  • delta(1)-Dehydrohydrocortisone
  • delta(1)-Hydrocortisone
  • Hydroretrocortine
  • Metacortandralone
  • PRDL
  • Prednisolona
  • Prednisolonum
UNII 9PHQ9Y1OLM
CAS number 50-24-8
Weight Average: 360.444
Monoisotopic: 360.193674006
Chemical Formula C21H28O5
InChI
InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
IUPAC Name
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0²,⁷.0¹¹,¹⁵]heptadeca-3,6-dien-5-one
Protein binding

Very high (>90%)

Toxicity

LD50=500 mg/kg (oral, rat), short-term side effects include high blood glucose levels and fluid retention. Long term side effects include Cushing's syndrome, weight gain, osteoporosis, glaucoma, type II diabetes and adrenal suppression.

Half life

2-3 hours

Delivery is an important issue, when it comes to online shopping. Our platform is customer-oriented, so we are constantly working on expansion of delivery destinations. It features an international shipping option, which lets customers from all around the world get quality and effective remedies fast. Also delivery is available to many cities in Australia, including the following:

  • Sydney
  • Albury
  • Armidale
  • Bathurst
  • Blue Mountains
  • Broken Hill
  • Campbelltown
  • Cessnock
  • Dubbo
  • Goulburn
  • Grafton
  • Lithgow
  • Liverpool
  • Newcastle
  • Orange
  • Parramatta
  • Penrith
  • Queanbeyan
  • Tamworth
  • Wagga Wagga
  • Wollongong